Abstract: Infant and child mortality rates reflect a country’s level of socio-economic development and quality of life and are used for monitoring and evaluating population and health programs and policies. This study examines the mortality of children under five using information from women’s birth histories pertaining to children born during the 10 years period before the survey by major divisions in Bangladesh, using data from the 1999-2000 Bangladesh Demographic and Health Survey (BDHS). Specifically, information is provided on levels, trends and differentials in neonatal, post-neonatal, infant and child mortality and assessing the effects of socio-economic, demographic and mother’s health-care characteristics on infant and child mortality. Mortality estimates are desegregated by urban-rural residence, division, mother’s education and antenatal care received and by selected demographic characteristics to identify segments of the population requiring special attention. This will help policy makers to formulate better policies in order to fight the current situation.