Population data on 6 short tandem repeat loci in a sample of Caucasian-Mestizos from Colombia

Type Journal Article - International journal of legal medicine
Title Population data on 6 short tandem repeat loci in a sample of Caucasian-Mestizos from Colombia
Author(s)
Volume 113
Issue 3
Publication (Day/Month/Year) 2000
Page numbers 175-178
URL http://link.springer.com/article/10.1007/s004140050293
Abstract
Blood samples from 409–452 unrelated Colombian
Caucasian-Mestizo individuals were amplified and
typed for six short tandem repeat (STR) markers
(HUMF13A01, HUMFES/FPS, HUMVWA, HUMCSF1PO,
HUMTPOX, HUMTH01). The allele frequencies, genotype
frequencies, heterozygocity, mean paternity exclusion
chance, polymorphism information content, discrimination
power, assumption of independence within and
between loci and Hardy Weinberg equilibrium were determined.
The results demonstrate that all markers conform
to Hardy-Weinberg equilibrium expectations. In addition,
the results demonstrate the assumption of independence
within and between the loci analysed. The mean exclusion
chance (MEC) was 0.9851 for all six STR loci analysed
and the discrimination power (DP) was 0.9999973. Therefore,
this Colombian population database can be used in
identity testing to estimate the frequency of a multiple
PCR-based locus DNA profile in forensic cases as well as
in paternity testing

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