The article presents an accurate scientific assessment of the physic-geographical, historical, socio economic and cultural assessment of Skënderbegas commune, Albania. The main purpose of this paper is to present these components in different time stages, by noting new qualitative elements. For the composition of this article we are based on a long observation and research work, across the geographical area of this commune, as well in terms of natural, demographic, cultural and economic aspect. An important role has had the numerous surveys have been conducted with the local residents, as well the use of an extensive literature related to subject of study. At first, it is provided a general assessment of the geographical position, landscape, geological construction, climate, hydrography, soils and vegetation. Further, it is made an analysis of the population of all the villages of the commune in question, highlighting the different rhythms the population from 1926 to 2013, and providing explanations for the decline in number of the reside each village. To demonstrate this performance, a chart is compiled, and respective analysis is done. An important place occupies the evaluation of patriotic and intellectual figures of this commune, their contribution to independence and freedom. Further it is made an assessment of the economy and lifestyle of these inhabitants, pointing out the problems that they have. At the end of the article are given the general conclusions and recommendations.