Agriculture is an essential driving force in the management of water use. Especially in Southern European countries, irrigation is an essential element of agricultural production and agricultural water use has a substantial share in total water use (exceeding 50%). The presented work contributes to the assessment of impacts of irrigated agriculture on water resources at European scale. We developed a modeling approach to estimate irrigation water requirements and regional irrigation water demands in the EU at high spatial resolution. The modeling approach was applied for a first assessment of irrigation water requirements.