Protective efficacy of BCG vaccine against leprosy in southern Malarwi

Type Journal Article - Epidemiol. Infect
Title Protective efficacy of BCG vaccine against leprosy in southern Malarwi
Author(s)
Volume 111
Publication (Day/Month/Year) 1993
Page numbers 21-25
URL http://www.researchgate.net/profile/Nguyen_Tam2/publication/14850231_Protective_efficacy_of_BCG_vacc​ine_against_leprosy_in_southern_Malai/links/0deec519cd25a840bd000000.pdf
Abstract
This paper describes a matched case-control study to determine the efficacy of BCG vaccine in preventing the occurrence of leprosy in southern Malawi, a previously unstudied area. The BCG immunization rate amongst 145 individuals with leprosy was 44-8%, compared to 62-5% in 290 matched controls. The protective efficacy of BCG vaccine against leprosy in this region was estimated to be 63-6 %; smallpox immunization had no effect. These findings support the view that BCG vaccine should be considered as a control measure in areas where leprosy is endemic.

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