This study aimed to analyze long-term urban land use (LU) change and its negative implications on the coastal environment of Iskenderun, Turkey. Information on urban LU change for the 144-year period between 1858 and 2002 was extracted from a historic city plan, black-white monoscopic aerial photographs, and Landsat ETM+ imagery. According to the results, areal extent of urban areas has increased approximately 40 times during the past 144 years. The population growth as a result of industrial developments and permanent migration was main driving force to the urbanization. Environmental problems that resulted from rapid development in the region such as air, water and soil pollution were highlighted and some recommendations were made in the light of qualitative and quantitative information on the urbanization and its negative consequences.