The birth of Islam over fourteen centuries ago was a monumental event in human history with an everlasting effect on humanity. For centuries researchers contemplated on the growth and distribution of Muslims throughout the World. The purpose of this manuscript is to present a reliable estimate of the Muslim population in Central America since the inception of Islam at the start of the 7th century to the start of the 24th century. The considered region consists of eight countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Mexico, Nicaragua and Panama. A centennial data estimate for these countries from 600 to 2300 (approximately 1H to 1700H) of the total population, and corresponding Muslim population and its percentage is provided. Furthermore, the same data in decennial order from 1790 to 2100 (or 1210H to 1520H) are provided for each country. These data are summarized to be a reference for other studies and discussions related to the Muslim population.