This report is one of four case studies—Turkey, Sahel, Ghana, and Peru—documenting the experiences of advocacy partner networks that have been formed or strengthened under the POLICY Project. The POLICY Project is a five-year, USAID-funded project designed to create supportive policy environments for family planning and reproductive health (FP/RH). POLICY is committed to forging a participatory policy process that involves more diverse and larger numbers of actors than the high-level decision makers traditionally involved in formulating and implementing policy. To this end, the project promotes the active and effective involvement of nongovernmental organizations(NGOs) and other representatives of civil society in policy advocacy to advance FP/RH policies that respond to the expressed needs of beneficiaries. POLICY stimulates the involvement of these new policy stakeholders by creating and strengthening advocacy networks. Worldwide, POLICY works with NGOs, women’s groups, professional associations, community-based organizations, and youth groups to transfer networking and advocacy skills and to enhance various groups’ ability to function as respected and credible legitimate partners in the policy arena.This Ghana case study is the fourth in the series and examines the environment in which the Eastern Region networks took root and the unique characteristics that have contributed to their success. It explores the relationship between the networks and thePOLICY Project and examines the achievements and challenges they both have confronted along the way. The experiences of these six networks reveal lessons that will help to expand and strengthen advocacy networks elsewhere in Ghana and around the world. The case study appendices include lists of contacts and network members.