Ghana’s Demographic and Health Surveys 1988 and 1993, and Ghana’s 1984 Population Census report were used to examine the effect of rapid population growth on 4 key sectors in Ghana. The population issue in Ghana concerns the high rate of growth and not the number of people. The rapidly increasing expenditure on education is associated with sharp increases in the proportion of eligible children attending school. Repeated pregnancies and births affect health conditions of child and mother while more people produce more waste causing additional stress on earth’s assimilative capacity. Three population projections were prepared using the Spectrum Computer Package from 1990-2020, each based on high, medium and low fertility and mortality assumptions as enumerated in Ghana’s National Population Policy. If fertility declines as assumed in the low fertility assumption, the population of Ghana will be 30.7 million by the year 2020, with the medium assumption, total population will be 33.6 million. However, with the high assumption, Ghana’s population will reach 35.2 million by 2020. These three population projections were subsequently employed to highlight the impact of population on Ghana’s Economic, Education, Health, and Environment sectors