Depriving children of the nutrients needed for growth sets them up to fail in life. When children are well nourished and cared for, they are more likely to survive, thrive, and to meaningfully contribute to society. This study assesses the association of characteristics of individual children under age five in Ghana, their mothers, and their households—as well as socioeconomic and environmental characteristics of the places where they live—with differential nutritional well-being. What distinguishes this study from most research on young children’s nutritional status in the Global South is its analysis of data for individual children, made possible by use of Demographic and Health Surveys (DHS), and assignation of district variables that capture characteristics of their places of residence to individual children as cases. This enables assessment of the relative explanatory role of variables that describe the socioeconomic and biophysical environments