The main objective of this study was to determine to what extent the students in the two Balkan countries are interested in starting their own business after graduating from institutions of higher education in the field of economics and business. Of key importance is exploring the opinion of students whether it is necessary the formal education to foster entrepreneurial skills through online programs in entrepreneurship. In addition, we wanted to determine the extent to which students are generally interested in e-learning and what they expect from that kind of education. In view of these and similar questions, we tried to do an analysis and compare the results of research on Turkey and Serbia. Our questionnaire contained eight questions to which the answers are provided by 100 participants from Turkey and 98 from Serbia. The two countries have taken for our study because they belong to Balkans region and therefore have certain characteristics that distinguish the region. Although there are some specific features of the region, the results showed significant differences between the two analyzed countries. Explanations can be found in the social, cultural, economic and other characteristics of Turkey and Serbia.