Several African countries instituted education reforms in the 1980s and 1990s. Yet, there is only little evidence on the effectiveness of these programs. Additionally, most previous studies of the determinants of literacy and numeracy have considered the proficiency in only one language and, possibly, numeracy. This paper examines both of these issues for the case of Ghana, analyzing the trends in and determinants of four different literacy skills and numeracy. A comparison of outcomes before and after the 1987 Education Sector Reform indicates that literacy and numeracy skills levels increased following the Reform, and more so for English literacy skills than for Ghanaian literacy skills, thus confirming prior expectations. The results from linear probability models of literacy and numeracy outcomes indicate that, consistent with the objective of the Reform, the productivity of primary education in terms of literacy and numeracy increased, while the productivity of other levels of education remained constant or decreased. Additionally, the results highlight the importance of school quality and other community level factors in the creation of literacy and numeracy and therefore also the importance of incorporating these factors in empirical analyses. The results indicate that the focus of the 1987 Education Sector Reform might have been too narrow, so that future education policy in Ghana may want to focus on strengthening the quality of education above the primary level, also.