In order to reduce morbidity and mortality resulting from poisoning by para-phenylenediamine
(PPD), we described the epidemiological and clinical characteristics associated with such poisoning and
determined the risk factors. For this purpose, we conducted a retrospective descriptive study of 102 cases
reported by the Moroccan Poison Control and Drug Monitoring Center between 1996 and 2007 in the Oriental
region. Based on the results, and with a sex ratio (men/women) of 0.9, the average age of the intoxicated
population was 17.3 ± 15.6 years. The most affected group age was of adults whom age is between 20 to 74
(40.2 %). The most encountered cases were voluntary poisonings, with 91.8 %. Suicidal attempts had
accounted for 99% of voluntary intoxication. The majority of the intoxicated had presented gastrointestinal
disorders. The evolution was favorable for 87 cases (85.3 %) and 15 cases had lost their lives; the lethality was
of 14.7 %. Following the analysis of the relative risk, age (less than 15 years / over 15 years) and origin of the
intoxicated (Urban / Rural) have been the main factors that influenced the prognosis. The relative risk being,
respectively, of 2.25 (95% CI: 1, 28-3, 95) and 3, 72 (CI95%: 1.70 - 8.13).