Objective. To estimate the disease burden of cancer in the
affiliate population of the Mexican Social Security Institute
(Instituto Mexicano del Seguro Social, IMSS) in 2010 by delega- tion. Materials and methods. The Disability-Adjusted
Life Years (DALYs), Years of Life Lost (YLL) due to premature
mortality and Years Lived with Disability/Disease (YLD) for 21
specific cancers and a subgroup of other malignant neoplasms
were calculated based on the methodology of the Global
Burden of Disease Study (GBD) for each of the 35 delega- tions of the IMSS. Results. In 2010, cancer represented the
fifth overall leading cause of disease burden in IMSS affiliates
(16.72 DALYs/1000 affiliates). A total of 75% of the cancer
disease burden in each delegation is due to ten specific
cancers, particularly breast cancer, which ranks first in 82%
of the delegations. Prostate cancer; tracheal, bronchial, and
lung cancers; leukemia, and colorectal and stomach cancers
occupy the second to fourth positions in each delegation.
With the exception of breast and prostate cancer, for which
the contribution of YLD to the DALYs was higher than 50%,
the greatest contribution to the DALYs of the other cancers
was premature mortality, which accounted for more than
90% of the DALYs in some cases. Conclusion. The results
obtained in this study allow for the identification of intervention
priorities with regard to cancer at the institutional level
and also for the focus at the delegation level to be placed
on cancers ranking in the top positions for disease burden.