Anogenital distance and umbilical cord testosterone level in newborns in Zaria, Northern Nigeria

Type Journal Article - Nigerian Journal of Physiological Sciences
Title Anogenital distance and umbilical cord testosterone level in newborns in Zaria, Northern Nigeria
Author(s)
Volume 26
Issue 1
Publication (Day/Month/Year) 2011
Page numbers 23-28
URL http://www.ajol.info/index.php/njps/article/viewFile/84887/74871
Abstract
The anogenital distance (AGD) is the distance between the anus and the base of the penis in males and anus to
fourchette (AF) distance in females and is a sexually dimorphic index that, on average, is twice as great in males as in
females, so it is used as an indicator of appropiate masculine development. In this study, the anogenital distance (AGD)
and anthropometric measurements such as birth weight, birth length, head circumference and placenta weight of 200
newborns (100 male, 100 female) were taken and umbilical cord serum was assayed for testosterone concentration using
Radioimmunoassay (Microwell). Data obtained were analysed using Student t-test and Pearson’s Correlation Analysis as
applicable. Results revealed that mean total anogenital distance was 22.53±0.70mm, and it was significantly higher in
males: 31.11±0.64mm than in females: 13.89±0.26mm and we observed that there was positive correlation between birth
weight and AGD in females. In males head circumference correlated positively with AGD. The mean cord testosterone
concentration was 2.78±0.30ng/ml in males and 2.09±0.22ng/ml in females and did not have any significant correlation
with anogenital distance. It was concluded that AGD of the population studied, though high was not significantly higher
than AGD in other parts of the world and umbilical cord testosterone level did not have any significant effect on AGD.

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