The mortality of children which has pneumonia and diarrhoea as some of its major causes remains a major concern for all countries of
which Ghana is no exception. Ghana’s current child mortality rate is far above the sustainable development goal 3.2. However, given that
vaccination is one of the most effective ways of preventing childhood diseases, it was surprising that, the 2014 Ghana demographic and
health survey (GDHS) report showed a falling up-take or coverage in the successive doses of the pneumococcal (pneumonia vaccine) and
rotavirus (diarrhoea vaccine) vaccines among children in Ghana. This study therefore using data from the children’s recode file of the
2014 GDHS, investigated the determinants of demand for subsequent doses of the pneumococcal and rotavirus vaccines for children in
Ghana by employing the binary probit model. The study among other findings revealed that, unemployed mothers were less likely to
demand for the subsequent and initial doses of both the pneumococcal and rotavirus vaccines for their children. Also male household
heads were revealed to be less likely to demand for all the doses of the rotavirus vaccines for children. In addition, single mothers were
also revealed to be less likely to demand for all the subsequent doses of the pneumococcal and rotavirus vaccines. Therefore targeting
unemployed and single mothers as well as women empowerment through job opportunities coupled with public education, especially of
household heads, would serve as effective tools in tackling the falling demand for subsequent doses of the pneumococcal and rotavirus
vaccines for children in Ghana.