The act of unauthorized siting of buildings has persisted in most developing countries. Despite numerous efforts at local levels to address this problem, its existence and effects keep on rising in various metropolises in Ghana. This research explores the causes of unauthorized siting of buildings in Asakae, a suburb of the Sekondi-Takoradi Metropolis, and suggests measures to curb them. In view of this, a sample size of 182 house-owners was chosen for the study. Accordingly, the sample size was determined using Fisher et al. formula and questionnaire survey approach was adopt- ed for the study. More so, data generated from the survey were further analyzed, using Relative Importance Index. The findings of the survey indicated that ignorance on planning and building regulations, inadequate housing schemes, unrealistic zonings and the location of land are critical variables which influence unauthorized siting of buildings. It is recommended that the populace should be given regular public education on land-use planning and the building regulations of Ghana. More so, the Assemblies should automate their systems, with respect to monitoring and detection of buildings under construction; so that buildings that were being located at unapproved places could be quickly detected, and appropriate measures could be taken before their completion.