Intimate Partner Violence (IPV) is a major public health problem estimated to affect 15–71% of women worldwide. We sought to elicit IPV risks among mothers of sick newborns in Ghana. As part of a broader study on postpartum depression, we conducted semi-structured surveys of 153 women in a mother-baby unit, assessing demographics, depression, social support, and IPV with the present partner. 46% of mothers reported some form of violence, mostly emotional (34%), followed by physical (17%) and sexual (15%). The study highlights the frequency of perinatal IPV and the associated risk factors of depression and poor social support.