The purpose of this study was to explore and describe the perception of nurses about the implementation of focused ante-natal care services in nine district health facilities of Dar es Salaam. Quantitative, explorative and descriptive research was conducted to determine how the implementation of the focused ante-natal care guidelines was perceived by nurses who provided midwifery health care services. Data collection was done using a structured questionnaire. A simple random sampling method was used to select the respondents. The study sample comprised of nursing officers (n=50), nurse midwives (53) and public health nurses (40). The SAS/Basic and SAS/STAT version 11.1 was used to analyse data. Validity was ensured and the Cronbach’s coefficient reliability test was 0.86.The findings revealed that the greatest area of concern was the shortage of human and material resources for successful implementation of focused ante-natal care to pregnant women and unborn children.