Micro-data from the 2009 Vietnam census indicate that lone mothers represent 11.0% of all women aged 15 to 49 living with at least one of their children (≤17 years old). Results from logistic regression models show that school enrollment and attainment levels are lower for children of lone mothers than for children living with two parents. This negative effect is observed for children of never married, divorced or separated, and widowed lone mothers as well as for children of women currently married to a migrant not residing in the household provided they are not head of household. This disadvantage may be explained by reduced availability of human, material, and financial resources; restricted agency of the mother; and long-term socioeconomic and demographic processes shaping family relations and migration.