An epidemiological investigation of risk factors for hypertension in Windhoek, Khomas region Namibia

Type Thesis or Dissertation - Master of Science
Title An epidemiological investigation of risk factors for hypertension in Windhoek, Khomas region Namibia
Author(s)
Publication (Day/Month/Year) 2017
URL http://repository.unam.edu.na/bitstream/handle/11070/2069/kaputjaza2017.pdf?sequence=1&isAllowed=y
Abstract
Hypertension is a major and preventable risk factor for cardiovascular diseases Khomas region
has a hypertension prevalence of 57%, which is the highest in Namibia. Cardiovascular diseases
related mortality is the highest among adults in Namibia. No analytical studies have been done to
determine risk factors for hypertension in Namibia. We conducted a study to determine lifestyle
and socio-demographic factors associated with hypertension in Khomas region.
We conducted an un-matched 1:1 case-control study in Khomas region. Anthropometric
measurements and a questionnaire were administered to both cases and controls. A case was
defined as any primary hypertension patient 18 to 60 years reporting to the selected health
facility. A control was defined as any person aged 18 to 60 years residing in the same
neighbourhood as the selected cases. Cases were selected using consecutive sampling from four
selected health facilities. Community controls were selected using simple random sampling. Bivariate
analysis was conducted to determine the odds ratios and 95% confidence level. Factors
which were significant at p-value less than 0.05 were retained in multiple logistic regression
model to determine significant associations.
A total of 131 cases and 131 community controls were interviewed. The mean (±SD) age of the
participants was 39.8 (±13.5) years. Overall, 184 (70.2%) of participants were female. Central
obesity was found to be associated with hypertension (OR=3.42, 95% CI=1.99 – 5.87, P = 0.001)
at the bivariate level. The multivariate analysis found that older age (OR = 1.08, 95% CI= 1.05 –
1.13, P = 0.001), attaining tertiary education (OR = 0.28, 95% CI= 0.08 – 0.92, P = 0.04) were
found to be protective against hypertension, while BMI ≥ 25 (OR = 2.29, 95% CI: 1.06 – 4.96, P
= 0.03) was significantly associated with hypertension.
Being Overweight/obesity and primary education are major risk factors for hypertension in
Khomas region. Interventions targeted at reducing obesity in the general population are needed to
curb the increase of hypertension.

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