This paper analyzes the changes of population by age and the gender structure in the regions of
the Republic of Macedonia. Age and gender is very important not only for the development of
demographic process but also for the development of regions. They play an important role in
planning the health care needs and other services with the socio-economic and cultural character.
In this sense they affect the performance of demographic processes (births, deaths, marriages, etc.)
and are a result of bilateral relations fertility, mortality, migration movements and other social
processes. The main objective of this paper is to identify the aging phenomenon of population in
state level and regions. This paper also dedicates special importance to the changes of age and sex
structure, during the period between1981-2014 in the regions of the republic of Macedonia.