This article aims to discuss the issues about Schistosoma japonicum infection in the Philippines based on the research findings of previous studies. This includes reviews about the nature of schistosomiasis, with emphasis on its effects on children. The review also discusses the mode of transmission of the parasite, etiology, and epidemiology, and relates these factors to the persistence of S. japonicum as a major health problem in the Philippines. The efforts, preventive measures, and recommended actions of the government are also mentioned and have been taken into consideration in strengthening the eradication measures against S. japonicum. This review further analyzes the risk factors associated with the infected individuals. Some measures and practices that may contribute to the prevention of S. japonicum infection are highlighted.