Thailand has come to an epidemiologic transition with decreasing infectious diseases and
increasing burden of chronic conditions, including cancer. Breast cancer has the highest incidence rates among
females throughout Thailand. This study aimed to identify the current burden and the future trends of breast
cancer of Lopburi, a province in the Central Thailand. Materials and Methods: We used cancer incidence data
from the Lopburi Cancer Registry to characterize and analyze the incidence of breast cancer in Central Thailand.
With joinpoint and age-period-cohort analyses, the incidence of breast cancer in the province from 2001 to 2010
and project future trends from 2011 to 2030 was investigated. Results: Age-adjusted incidence rates of breast
cancer in Lopburi increased from 23.4 to 34.3 cases per 100,000 female population during the period, equivalent
to an annual percentage change of 4.3% per year. Both period and cohort effects played a role in shaping the
increase in incidence. Joinpoint projection suggested that incidence rates would continue to increase in the future
with incidence for women ages 50 years and above increasing at a higher rate than for women below the age
of 50. Conclusions: The current situation where early detection measures are being promoted could increase
detection rates of the disease. Preparation of sufficient budget for treatment facilities and human resources, both
in surgical and medical oncology, is essential for future medical care.