Background: Thailand currently faces significant rise of aging population which has become an important public health issues. The objective of the study was to assess the background profile, pa ern of disease and overall health related quality of life (HRQOL) of elderly population residing in Bungsan sub-district of Nakhon Nayok province in rural Thailand. Methods: Data were collected from 148 elderly population (male=67, female =81) aged over 60 years of old. SF 36 was used for the data collection by the trained interviewers. The dependent variable of this study was health related quality of life (HRQOL) which was measured using two sub-components of SF 36 - one is Physical Component Summary (PCS) and another is Mental Component Summary (MCS). Results: Multiple logistic regression analysis revealed that the older persons suffering from chronic diseases are more prone to low quality of life in health both in PCS and MCS [OR: 7.92, CI: (4.89-15.88) and OR: 1.94, CI (1.24-3.11) respectively]. Further, the individual aged more than 75 years puts high risk of decreasing HRQOL in both PCS and MCS ([OR: 2.71, CI: (1.90-3.83) and OR: 1.74, CI: (1.23-2.08) respectively] than 60-75 years of old persons. Additionally, the women and illiterate possessed an increase in low PCS than that of men and literates [OR: 1.29, CI: (1.02-1.85) and OR: 1.72, CI: (1.20-2.35) respectively]. Conclusion: The study fi ndings suggest that the older person gets more decrease in HRQOL with increase in age. Also, some other factors such as gender, illiteracy and chronic diseases have an important role towards decrease in HRQOL among more aged population.