In the Tonle Sap Lake Region, Cambodia, the interconnections between migration, environment and all water resources are apparent. These interconnections have not been widely studied in Cambodia, even though the study of water related migration could yield important socio-economic information for the development aims of the Mekong Basin, the urbanization trends, and the future problems in the poor settlements of Phnom Penh. Due to the knowledge gap, this paper explores the push that drives population from the Tonle Sap Lake and its linkages with environment and water. This study examines water-related migration from the major lake in Cambodia by literature reviews and participatory field studies.