The vulnerability of the youth, in terms of unemployment, in Northern Ghana is manifest by persistent migration streams to Southern Ghana and its attendant negative effects, such as high crime rate. Vocational skills development has been identified as one effective means of tackling the unemployment problem of the area, which could ultimately reduce the inherent migration trends. This paper analyses the effectiveness of a vocational skills development model in tackling unemployment and migration by the Social Investment Fund in the Northern and Upper East Regions of Ghana. The study revealed the usefulness of the initiative in terms of employment generation and reduction of out-migration through the cost effective utilization of master craftsmen as trainers. The sustainability of such programs can be guaranteed through the establishment of an enabling environment for effective private sector participation.