Prevalence of Antibodies Against Foot-and-Mouth Disease Virus in Cattle in Kasese and Bushenyi Districts in Uganda

Type Journal Article - International Journal of Animal and Veterinary Advance
Title Prevalence of Antibodies Against Foot-and-Mouth Disease Virus in Cattle in Kasese and Bushenyi Districts in Uganda
Author(s)
Volume 2
Issue 3
Publication (Day/Month/Year) 2010
Page numbers 89-96
URL http://agris.fao.org/agris-search/search.do?recordID=DJ2012057783
Abstract
The aim of this study was to determine the seroprevalence and serotype-specificity of the circulating antibodies against Foot-and-Mouth Disease Virus (FMDV) in cattle in Kasese and Bushenyi districts in Uganda. A total of 309 serum samples were collected and tested for antibodies against Non-Structural (NS) and Structural Proteins (SP) using Ceditest® FMDV-NS and Ceditest® FMDV type O test kits. Seroprevalences were much higher in Kasese in both tests (61 and 43%, respectively) than in Bushenyi (3 and 4%, respectively). A high proportion of sera, that tested positive in the NSP test, were subjected to seven serotype specific blocking ELISAs for antibodies against the seven FMDV serotypes (O, A, C, Asia 1, SAT 1, SAT 2 and SAT 3). The study showed presence of antibodies against four FMDV serotypes with decreasing magnitude as follows: O> SAT 1> SAT 3/SAT 2. It is recommended to develop sampling schemes to include virus recovery and identification, as well as to focus serum sampling on young unvaccinated stock.

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