|Type||Journal Article - BMC Pediatrics|
|Title||Predictors of oedema among children hospitalized with severe acute malnutrition in Jimma University Hospital, Ethiopia: a cross sectional study|
Severe acute malnutrition has two main clinical manifestations, i.e., oedematous and non-oedematous. However, factors associated with oedema are not well established.
Children 0.5-14 years of age with SAM (MUAC 11.0 cm or weight-for-height 70 % of median and/or nutritional oedema) admitted to the nutrition unit were included. Information on infections before and during admission was collected together with anthropometry. Predictors of oedema was analysed separately for younger (60 months) and older children (=?60 months).
351 children were recruited (median age: 36 months (interquartile range 24 to 60); 43.3% females). Oedema was detected in 61.1%. The prevalence of oedema increased with age, peaked at 37–59 months (75%) and declined thereafter. Infection was more common in the younger group (33% vs. 8.9%, p?0.001) and in this group children with oedema had less infections (25.2% vs. 45.1%, p?=?0.001). In the older group the prevalence of infections was not different between oedematous and non-oedematous children (5.5% v. 14.3%, p?=?0.17). In the younger group oedema was less common in children with TB (OR?=?0.20, 95% CI: 0.06, 0.70) or diarrhea (OR?=?0.40, 95% CI: 0.21, 0.73).
The proportion of oedema in SAM peaked at three to five years of age and a considerable proportion was above 5 years. Furthermore, the prevalence of infection seemed to be lower among children with oedema. Further studies are needed to better understand the role of infection-immunity interaction.
|»||Ethiopia - Demographic and Health Survey 2011|