The family is the basic unit of human life. Changes in family life cycle may have positive or negative effects on the members and the society. This study examined the management of changes in the family life cycle of people in Mankessim. Descriptive research design was used for the study. Based on multi-stage sampling procedure, 150 families were studied. The study revealed that the major changes that the families went through were job loss, moving to a new location, arrival of a new member, illness and accidents and job change. These changes affected the families in several ways such as increase in expenditure, emotional stress on individuals and time constraints to adjust. It was recommended that families should involve all members in decision-making and implementation processes to help manage these changes. Also, families should be more open to interact in order to gain much information on how to manage affairs.