This paper reflects on how the city of Manizales, Colombia, is incorporating climate change adaptation into its plans, and how this can build on the foundations of the city’s long-established urban environmental policy (Biomanizales) and local environmental action plan (Bioplan) that have guided urban development and have developed incorporating disaster risk reduction into local development policies and local land use plans. The success is rooted in coherent, multi-level governance, including capacity to integrate disaster risk reduction, climate change adaptation, land use and territorial planning within a holistic view of development that includes the views and capacities of multiple stakeholders. As the process matures, an acknowledgment of weaknesses leads to improved ways of addressing climate-related risks and adaptation challenges.