Abstract The following objectives were set for this thesis: 1. To investigate the appropriateness of the LittlEARS® Auditory Questionnaire as a screening tool for hearing loss and other related educationally significant disorders in Ghanaian children aged 4 - 36 months. 2. To adapt and evaluate the multiple Frequency Animal Sound Test (mFAST) as an alternative to pure tone audiometry in screening children. 3: To construct, norm and validate four (4) language versions (Asante, Akuapem, Fante and Ghanaian English) of the Adaptive Auditory Speech Test (AAST) in quiet and in noise. In order to attain the set objectives, six (6) research questions were raised. Design: A cross- sectional design was used to select a total of 1820 participants for the study. This sample included parents, younger and older children as well as adults. For validation of LittlEARS® Auditory Questionnaire, norm data were collected for N=448 children. The effect of ‘administration mode’ was investigated by collecting data from N=152 parents (respondents) and the feasibility of using LittlEARS® Auditory Questionnaire as a screening tool between 24-36 months was investigated by collecting data from N=513 respondents. Validation data for mFAST were collected from N=45 students aged between 20 and 30 years with normal hearing. In order to determine the Akan AAST norm, data were collected from (N=581) children who spoke Asante, Akuapem and Fanti as their native language. Finally, in order to determine learning effects data were collected from (N= 81) children. Results: Results show that the Ghanaian and German norm curves are comparable and it does not make any difference whether LittlEARS® Auditory Questionnaire is administered via self administration or by interview. The data also supports the use of the LittlEARS® Auditory Questionnaire to screen for hearing loss in Ghanaian infants and children from 4 months old up to the age of 3 years. Overall the results support the proposition that the LittlEARS® Auditory Questionnaire, the multiple Frequency Animal Sound Test (mFAST) and the Adaptive Auditory Speech Test (AAST) are appropriate tools for the early identification of Ghanaian children with hearing loss.