The Methodist Church is known for its Class System. It is an important discipleship process which all members in the church are required to be part of. It is a response to the Great Commission found in Matthew 28:18-20. The exegesis of the text revealed that the main command is ?make disciples? whilst ?going?, ?baptising?, and ?teaching? are participles supporting the main command. Making disciples encompasses evangelism and establishing the members won which would result in both qualitative and quantitative growth. The study is conducted at the Effiduase Diocese of Methodist Church Ghana (MCG) through the administration of questionnaire, interviews and examination of the Diocesan statistical reports. A number of relevant written materials such as biblical commentaries and handbooks were consulted. The research has revealed that Matthew 28:18-20 concept of discipleship and the Class System as practised by the Effiduase Diocese of MCG together with the use of Weekly Bible Lessons have improved biblical understanding of the members and some social issues as well. It further revealed that the numerical growth of the Diocese is low since the Diocesan growth rate of one point two percent (1.2%) is below national growth rate of two point five percent (2.5%) against the backdrop of the Church‘s own projection of twenty percent (20%) yearly growth rate from 2004 to 2009. The study recommends intensification of outreach programmes and attendance to Class Meetings. These would ensure qualitative and quantitative growth of the Diocese.