Women comprise almost half of the world’s population. Almost same in number with men, they are discriminated socially, politically and economically in many ways. Women’s participation in socio-cultural, economic and political activities is essential for their economic sustainability, household maintenance as well as to heighten their independence. Socio-political and economic constraints to women’s empowerment exist in most of the world societies. However, the nature and shape of these constraints differ from culture to culture and society to society. This study was undertaken on socio-political and economic constraints in women’s empowerment in Pakhtun Society of Chakdara District Dir (L) Khyber Pakhtunkhwa Pakistan. Women in the region have been discriminated in many ways, i.e. at domestic, economic, religious and political levels. To investigate socio-political and economic constraints, the researcher ethnographically selected village Chakdara and a survey of 4331 household was conducted. Data was collected from 176 educated respondents by systematic random sampling technique using semi-structured interview schedule. The collected information has been classified, tabulated and presented in bar charts, which has further been discussed qualitatively in detail. The study highlights that there exist various social, political and economic barriers to women’s empowerment. However, changes are observable in gender roles towards women’s participation in socio-cultural activities and the need is to provide educational opportunities, gender representation in government policies and programs and socialization.