Women’s participation in the economy, as integral part of their empowerment, is amajor challenge facing the MENA-region, since women’s labour market participation(LMP) is among the lowest throughout the world in these countries. Nonetheless, on abroad comparative scale, the determinants of women’s LMP in this region are understudied, especially the interplay between them. We use representative data covering over 50,000 women and over 65 districts within five MENA-countries (Egypt,Jordan, Morocco, Syria and Tunisia). On these data we apply multilevel logisticregression analysis with women’s formal LMP as dependent variable and individual level characteristics (e.g. age, education), household information (e.g. husband’s education and occupation, number and age of children), district characteristics (e.g.,level of development, labour market structure, culture) and account for differences at the national level. By doing this we show the importance of encompassing views; in understanding women’s LMP different levels, domains and conditions are important. And interactions between these levels and factors give more insight in the complex matter.