The effects of lime, wood ash, manure and mineral P fertilizers on the growth of wheat (Triticum aestivum L.) and selected soil chemical properties related to acidity were investigated in a pot experiment and an in incubation study on a kaolinite rich, high P fixing and strongly acidic soil (pH 4.9) of Farta District. Four rates of lime and wood ash (3.5, 7.0, 9.2 and 11.2 tons CaCO3 equivalents ha-1) were separately applied to obtain target soil pH values of 5.5, 6.0, 6.5 and a lower pH obtained with half of the lime requirement needed to bring the pH to 5.5. Three rates of mineral P fertilizer and manure P (32.5, 65 and 130 kg P ha-1) were uniformly applied separately into the whole soil volume. To mimic localized application, the mineral P rates were also applied into 2 and 5% of the soil volumes. The impact of P additions on solution P concentration was estimated with a quantity-intensity (Q/I) plot. Wood ash and lime (7 tons CaCO3 equivalents ha-1) were combined separately with each of the manure P and mineral P rates as additional treatments. Incubation of the soil with the different rates of lime, wood ash, manure and manure plus 7.0 tons of CaCO3 ha-1 lime or wood ash for 60 days before sowing significantly increased the available Olsen P and pH and decreased the exchangeable acidity and Al compared to the control treatment. The plant height, dry shoot biomass and P uptake of wheat increased significantly (P = 0.001) by the application of the treatments except manure compared to the control. Application of mineral P plus wood ash (130 kg P ha-1 + 7.0 tons CaCO3), wood ash (11.2 tons CaCO3 ha-1) and mineral P plus lime (130 kg P ha-1 + 7.0 tons CaCO3) increased plant height by 40, 41 and 45%; dry shoot biomass by 131, 142 and 168%; P uptake by 138, 156 and 177%, respectively, compared to the control. The mineral P plus lime also gave the highest apparent P recovery compared to the other treatments. Compared to application of 130 kg P ha-1 to the whole soil volume and the control treatment, the localized mineral P application to 2% soil volume at 130 kg P ha-1 increased dry shoot biomass by 21 and 101% and P uptake by 24 and 106%, respectively. This positive effect of localized application is explained by the Q/I plot. Localized application of the highest P rate elevated the solution P concentration initially to 5.3 mg L-1, promoting P uptake, while in uniform application solution P concentration remained at 0.1 mg L-1 well below the critical solution P concentration. Application of either wood ash alone, mineral P fertilizer plus lime or wood ash or localized applications of mineral P to a very small soil volume can be recommended to achieve a better growth and P uptake of wheat in acid soils of Farta District which are low in available P and have a high P fixation tendency.