Poverty trends in Ghana show a decline over the last two decades. However, the period also shows evidence of the intensification of vulnerability and exclusion among some groups, including women. Among several variables accounting for women’s vulnerability to poverty are gender inequalities, which it is argued, undermines development and the prospects for improving standards of living. Therefore it has been suggested that policies, which aim at reducing poverty and promoting sustainable development must integrate gender equality, equity and women’s empowerment in its goals. Despite these, the interconnections between a reduction in gender inequality and a reduction in poverty are complex. The paper explores the gender dimensions of poverty in Ghana, and how gender inequalities are manifested and implicated in the reproduction of poverty. It also assesses the extent to which these have been taken into account in poverty reduction strategies and policies to enhance the situation of women. It concludes that if strategies to engender poverty reduction programmes are to be sustainable it is important to recognize unequal gender relations and the structures of power that women confront at all levels in Ghana and how these increase women’s vulnerability to poverty.