Background: Trend and Pattern of stomach
cancer vary in different geographical regions. Some
of studies indicated that there is a relationship between
stomach cancer and Socio economic status.
The aim of this article is the study of the trend of
stomach cancer in over time, and also the effect of
economical factors on cancer incidence in Iran.
Materials and Methods: In this study, various
sources of data were obtained through National Cancer
Registry (2003-2010) and Statistical Center in
Iran. Trend of cancer rate was estimated adjusted for
sex, age groups and patient’s residential locations.
A proxy value was calculated for all individuals
using principal components analysis (PCA).The
risk of cancer based on the population and score
was assessed. This model controlled for different
age groups and provinces in separate gender. All
analysis done with Software stata 12.
Result: From the notional cancer registry of
Iran, 49276 cases stomach cancer were obtained between
2003 and 2010.Age-standardized incidence
rates were generally higher in men than in women
and its trend vary in different provinces in Iran.
The negative binomial regression model
showed risk of cancer incidence for men and
women were 60% and 52%. All of age groups
under 45 years had a lower risk. The highest IRR
attributed to year 2008 for each sex. Our results
showed, there is an Inverse relationship between
stomach cancer and economic status in Iran.
Conclusion: Incidence of gastric cancer had an
increasing trend in both sexes and economic status
has a negative relation with incidence of gastric
cancer. We believed further research in future is
needed into the relation between ES and gastric
cancer, especially based on individual data to
avoiding ecological fallacy