To the east of Morocco (Oriental region), carbon monoxide poisoning is frequent, serious and often
unrecognized. It is a public health problem whose prevention proves to be necessary. The present study aims
to describe the main epidemiological and clinical characteristics of patients poisoned by carbon monoxide, and
to determine factors that may have influenced the evolution of these patients. This epidemiological study
included 2012 cases of carbon monoxide poisoning reported between 1992 and 2011 by the Moroccan Poison
Control Pharmacovigilance Center (CAPM). The mean age of poisoned patients was 26.9 ± 16.7 years, the sex
ratio (F/M) was 2.2. The poisoning was accidentally occurred in 99.5% of cases, especially at the place of
residence (98.3%). The maximum of declarations was observed during cold months. The urban population was
the most affected (95.1%). The region of Oujda-Angad was the most concerned with 68.1% of cases. Patients
with symptomatic state represented 89.2%. Symptomatology was characterized by the predominance of
dyspnea, cephalgia, vertigo, tachycardia respectively 26.7%, 17.2%, 16.1%, and 10.5%. The period of
consultation was 09 ± 28 hours. Deaths reached a percentage of 1.3%. The effect study of parameters on the
evolution of the health status of patients showed that sex, poisoning type (Isolated, collective) and clinical
status (symptomatic, asymptomatic) are associated with the evolution of patients: The relative risks were
respectively (OR = 1.53, p = 0.008), (OR = 2.34, p = 0.017), and (OR = 3.02, p = 0.001).
The epidemiological profile of carbon monoxide poisoning in the Oriental region justifies the implementation of
awareness campaigns near the population of this region in order to reduce the incidence and to allow rapid
and adapted taking of charge in the case of accident.