Background: Reports reveal deficiencies in the knowledge of women related issues in epilepsy, among health care
professionals, with consequent inadequate health education and poor health care delivery to this set of patients.Aim:
To assess the knowledge of women`s issues in epilepsy among residents at the University of Calabar Teaching
Hospital, Nigeria.Method: Seventy two consenting residents from the Internal medicine, Family Medicine and
Obstetrics & Gynecology departments of the hospital, were requested to complete the KOWIE II questionnaire
designed to assess knowledge of women`s issues in epilepsy. Results: One fifth of the respondents knew about the
effects of sex hormones on seizures. Two fifths knew of the higher incidence of sexual dysfunction among women
with epilepsy, the undesirable effects of anti-epileptic drugs (AEDs) on bone health, and the best choice of antiepileptic
drug in pregnancy. Two thirds knew of reduction in contraceptive efficacy by some AEDs, and the need to
administer vitamin K to neonates of women on AEDs. Four fifths knew that women on AEDs should be given folic
acid, and that majority of women with epilepsy have healthy children. Half of the respondents knew that women on
AEDs can safely breast feed. The overall mean KOWIE II score was 56.7%. Conclusion: The Residents were poorly
informed about the issues affecting women with epilepsy. There is need for continuing medical education efforts to
bridge the gap in knowledge.