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Citation Information

Type Journal Article - SAGE Open Medicine
Title Characteristics, risk factors and case fatality rate of stroke in hospitalized patients in semi-urban South - South Nigeria
Author(s)
Volume 1
Publication (Day/Month/Year) 2013
URL http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687779/
Abstract
Background:

Stroke causes death and disability worldwide. Hypertension is the most prevalent risk factor. In Nigeria, studies on outcome and risk factors of stroke are from urban-based hospitals. This study aims to look at stroke outcome and the major modifiable risk factors of hospitalized stroke patients in semi-urban Nigeria.

Methods:

The medical records of stroke patients admitted between March 2008 and February 2010 were reviewed retrospectively. The relevant demographic, clinical and laboratory data of each patient were retrieved.

Results:

A total of 99 cases of stroke made up of 51 males and 48 females were reviewed. Mean age of the subjects was 66.22 ± 12.67 years. Mean systolic blood pressure and diastolic blood pressure at presentation were 171.41 ± 39.10 mmHg and 100.44 ± 21 mmHg, respectively. About 61.6% were known hypertensives, while 31.3%, not previously known to be hypertensive, had SBP = 140 mmHg and/or diastolic blood pressure = 90 mmHg. Overall, 85.9% of the subjects had SBP = 140 mmHg and/or DBP = 90 mmHg. In all, 46.5% had SBP = 180 mmHg, and 63% of this number had SBP = 200 mmHg; 42.4% had DBP = 110 mmHg. Other major risk factors were hypercholesterolaemia (34.4%), diabetes mellitus (16.6%), previous cerebrovascular accident (15.2%) and smoking (9.4%). In all, 31.3% had two or more modifiable stroke risk factors. 36.4% of the subjects were comatose. Overall case fatality rate was 45.8%, 75% of the subjects with coma died, compared to 27.6% without coma (p < 0.01).

Conclusion:

Mortality in our stroke patients is high. Hypertension is the commonest modifiable risk factor, and the presence of coma at presentation is associated with poor prognosis.

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