The continual cases of new HIV/AIDS infections in San communities is an issue of grave
concern. Given that the information aimed at sensitizing these communities was disseminated
in English and Setswana and most of San people spoke only San languages, it was
hypothesized that languagebarrier could be contributing to inadequate knowledge about
HIV/AIDS in San communities.Based on this problem, this paper examines how failure to
use the San and other languages spoken by the San could have contributed to resistance to
HIV/AIDS health promotion by some San people in the Central District. Using a semistructured
interview withrandomly selected four San couples at Moitshopari cattle-post, this
paper examines the San couples‟ behaviors and their response towards HIV/AIDS campaigns.
The findings indicated that the Sanwere living in a different and peculiar communication
environment which did not accord with the communication processes of HIV/AIDS health
promoters. Data were interpreted and analyzed through a careful consideration of the cultural
context of the San where it wasproduced. The conclusion is that despite all the efforts made
to sensitize Botswana populationon HIV/AIDS health, failure to address HIV/AIDS issues in
the languages spoken by alltarget audiencesmade the campaigns ineffectual.