Background: Anemia is a leading cause of maternal death in the world. About half of it occur in southeast Asia and
among them, 80% occur in India. Nowadays, intravenous (IV) iron sucrose is started for the therapy of severe anemia.
Objective: This study was done to evaluate the adverse effect and compliance of IV iron sucrose injections in ante- and
post-natal women. Materials and Methods: Totally 406 patients having hemoglobin between 4 and 7 g/dL were included
in the study. IV iron sucrose was started as per the national guidelines. At every follow-up visit, patients were examined
and asked about adverse effects. The number of patients lost to follow-up was recorded, and the patients were contacted on
phone about adverse effects. Recorded data were entered in MS Excel 2016. Chi-square test was used for analysis, and the
results were published as percentage. Results: The most common adverse effect experienced by women was swelling at
injection site (8.87%) followed by muscle/joint pain (2.7%) and pruritus (2.7%). Anaphylaxis was observed in <0.5% of the
patients. Multiparous women and postnatal women were less compliant to treatment. Conclusion: IV iron sucrose is very
safe, and the adverse effects are minimal. Compliance is less in multipara and postnatal women as compared to primipara
women. Hence, proper counseling is needed mainly for multipara and postnatal women to improve their compliance to
treatment.