Etiology of cervical cancer (C53) in Central and South America

Type Journal Article - International Agency for Research on Cancer. Available from: http://www-dep. iarc. fr/CSU\_resources. htm
Title Etiology of cervical cancer (C53) in Central and South America
Author(s)
Publication (Day/Month/Year) 2016
URL http://gco.iarc.fr/includes/CSA_Chp_4-9_Cervix.pdf
Abstract
Persistent infection of the cervix with high-risk types of human papillomavirus (HPV)
has been established as a necessary (but not sufficient) cause for the development
of cervical cancer [1]. Evidence suggests that HPV infection precedes the
development of cervical cancer by several decades and that persistent infection with
HPV is necessary for the development and progression of pre-cancerous lesions of
the cervix, either to higher grades of pre-cancerous disease or to invasive cancer – a
process that can take 10–30 years [2].

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