|Type||Journal Article - International Journal of Epidemiology|
|Title||Estimates of the burden of mortality directly attributable to malaria for children under 5 years of age in Africa for the year 2000 Final report|
Background Although malaria is a leading cause of child deaths, few well-documented estimates of its direct and indirect burden exist. Our objective was to estimate the number of deaths directly attributable to malaria among children <5 years old in sub-Saharan Africa for the year 2000.
Methods We divided the population into six sub-populations and, using results of studies identified in a literature review, estimated a malaria mortality rate for each sub-population. Malaria deaths were estimated by multiplying each sub-population by its corresponding rate. Sensitivity analyses were performed to assess the impact of varying key assumptions.
Results The literature review identified 31 studies from 14 countries in middle Africa and 17 studies and reports from four countries in southern Africa. In 2000, we estimated that ~100 million children lived in areas where malaria transmission occurs and that 803?620 (precision estimate: 705 821–901 418) children died from the direct effects of malaria. For all of sub-Saharan Africa, including populations not exposed to malaria, malaria accounted for 18.0% (precision estimate: 15.8–20.2%) of child deaths. These estimates were sensitive to extreme assumptions about the causes of deaths with no known cause.
Conclusions These estimates, based on the best available data and methods, clearly demonstrate malaria's enormous mortality burden. We emphasize that these estimates are an approximation with many limitations and that the estimates do not account for malaria's large indirect burden. We describe information needs that, if filled, might improve the validity of future estimates.
|»||Angola - Multiple Indicator Cluster Survey 2001|
|»||Benin - Enquête Démographique et de Santé 2001|
|»||Congo, Dem. Rep. - Enquête à Indicateurs Multiples 2001|
|»||Ethiopia - Demographic and Health Survey 2000|
|»||Gabon - Enquête Démographique et de Santé 2000|
|»||Gambia, The - Multiple Indicator Cluster Survey 2000|
|»||Ghana - Demographic and Health Survey 1998|
|»||Guinea-Bissau - Multiple Indicator Cluster Survey 2000|
|»||Kenya - Demographic and Health Survey 1998|
|»||Malawi - Demographic and Health Survey 2000|
|»||Mali - Enquête Démographique et de Santé 2001|
|»||Nigeria - Demographic and Health Survey 2003|
|»||Rwanda - Enquête Démographique et de Santé 2000|
|»||Senegal - Enquête à Indicateurs Multiples 2000|
|»||Sierra Leone - Multiple Indicator Cluster Survey 2000|
|»||Tanzania - Reproductive and Child Health Survey 1999|
|»||Uganda - Demographic and Health Survey 2000-2001|