This chapter aims to contribute to the understanding of the relationship among law, and more specifically commercial law, development and innovation in low-income countries. It examines how this relationship unfolds in the female micro-entrepreneurial sector in Africa. Innovative business practices were investigated through semi-structured interviews in Benin, Cameroon and Côte d’Ivoire. Moreover, the chapter analyses some particularities of the OHADA regime in order to assess how they affect entrepreneurial innovation in the environments in which the respondents trade. The conclusion makes preliminary recommendations on the manner in which commercial law reform can help overcome the obstacles to female micro-entrepreneurial innovation.