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Citation Information

Type Journal Article - Human genomics
Title Identification of a novel cytosolic aldehyde dehydrogenase allele, ALDHIAI* 4
Author(s)
Volume 3
Issue 4
Publication (Day/Month/Year) 2009
Page numbers 1
URL http://humgenomics.biomedcentral.com/articles/10.1186/1479-7364-3-4-304
Abstract
This paper reports the identification of a novel cytosolic aldehyde dehydrogenase 1 (ALDHIAI) allele. One hundred and sixty-two Indo-Trinidadian and 85 Afro-Trinidadian individuals were genotyped. A novel ALDHIAI allele, ALDHIAI*4, was identified in an Indo-Trinidadian alcoholic with an A inserted at position -554 relative to the translational start site, +1. It was concluded that a wider cross-section of individuals needs to be evaluated in order to determine the representative frequency of the allele, and to see if it is associated with risk of alcoholism.

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