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Type Journal Article - Middle East Journal of Digestive Diseases (MEJDD)
Title A population-based seroepidemiological study on hepatitis E virus in Iran
Volume 2
Issue 2
Publication (Day/Month/Year) 2010
Page numbers 97-103
URL http://www.mejdd.org/index.php/mejdd/article/download/360/483
Little is known about HEV seroprevalence and its determinants
in Iran. Considering the fact that Iran is among the countries in
which HEV infection is endemic, a large-scale population-based
study in this regard is justified.
This survey was conducted in 2006 in Tehran and Golestan Provinces,
Iran. Stored sera of subjects were tested for serological
markers of anti-HEV. The baseline data were recorded in structured
questionnaires. Weighted seroprevalence and weighted logistic
regression coefficients were calculated.
A total of 1423 samples were included. The overall seroprevalence
in two provinces was 7.4%. Age with an odds ratio equal to
1.59 (95% CI: 1.26-2.02) and history of traditional phlebotomy
with an odds ratio equal to 2.28 (95% CI: 1.13-4.60) were independent
predictors of HEV seropositivity.
Considering the high rate of HEV seroprevalence in Iran, further
studies on the cost-effectiveness of vaccination among vulnerable
groups are mandatory

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