FHTTP/1.1 200 OKServer: nginx/1.12.2 Date: Mon, 27 Jan 2020 16:06:53 GMT Content-Type: text/html; charset=UTF-8 Transfer-Encoding: chunked Connection: keep-alive X-Powered-By: PHP/7.2.24 Set-Cookie: ihsn_nada=si80o7lf7r7n07rke5qond8uans8vcqn; expires=Mon, 27-Jan-2020 18:06:53 GMT; Max-Age=7200; path=/; HttpOnly Pragma: no-cache Cache-Control: no-cache, must-revalidate Expires: Sat, 26 Jul 1997 05:00:00 GMT 1ec8 Prevalence and incidence of cervical intra-epithelial neoplasia among female sex workers in Korogocho, Kenya

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Citation Information

2000
Type Journal Article - Public Health Action
Title Prevalence and incidence of cervical intra-epithelial neoplasia among female sex workers in Korogocho, Kenya
Author(s)
Volume 3
Issue 4
Publication (Day/Month/Year) 2013
Page numbers 271-275
URL http://www.ingentaconnect.com/contentone/iuatld/pha/2013/00000003/00000004/art00004?crawler=true&mim​etype=application/pdf
Abstract
SETTING: Sex Workers Outreach Programme Clinic, Korogocho, Nairobi, Kenya.

OBJECTIVE: In a cohort of sex workers, to determine 1) the prevalence of cervical intra-epithelial neoplasia (CIN) and its association with human immunodeficiency virus-1 (HIV-1) infection, and 2) the incidence rate of CIN during the 3-year follow-up from December 2009 to December 2012.

DESIGN: Prospective nested cohort study.

RESULTS: Of the 350 women enrolled, the median age was 29 years (range 18–49); 84 (24%) were HIV-1-infected. At enrollment, 54 (15%) had an abnormal cytology, 39 (11%) had low-grade intra-epithelial lesions (LSIL) and 15 (4%) high-grade intraepithelial lesions (HSIL). HIV-1-infected women were 2.7 times (95%CI 1.7–4.4) more likely to have CIN than non-HIV-1-infected women. Among HIV-1-infected women, the prevalence of LSIL and HSIL was 2.5 times (95%CI 1.2–5.1) and seven times (95%CI 2.3–23.3) greater than among non-HIV-infected women. During the follow-up period, 39 (11%) women had incident CIN (6.6/100 person years [py]), with no difference by HIV status, i.e., respectively 7.9/100 py and 6.3/100 py in HIV-1-infected and non-HIV-1-infected women.

CONCLUSION: The prevalence and incidence of CIN among HIV-1-infected sex workers was high; early, regular screening and follow-up of this life-threatening condition is therefore recommended.

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