Epidemiology and risk factors for pneumonia severity and mortality in Bangladeshi children< 5 years of age before 10-valent pneumococcal conjugate vaccine introduction

Type Journal Article - BMC public health
Title Epidemiology and risk factors for pneumonia severity and mortality in Bangladeshi children< 5 years of age before 10-valent pneumococcal conjugate vaccine introduction
Author(s)
Volume 16
Issue 1
Publication (Day/Month/Year) 2016
URL https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-016-3897-9
Abstract
Background
Pneumonia is the leading infectious cause of morbidity and mortality in young children in Bangladesh. We present the epidemiology of pneumonia in Bangladeshi children <5 years before 10-valent pneumococcal conjugate vaccine introduction and investigate factors associated with disease severity and mortality.

Methods
Children aged 2–59 months admitted to three Bangladeshi hospitals with pneumonia (i.e., cough or difficulty breathing and age-specific tachypnea without danger signs) or severe pneumonia (i.e., cough or difficulty breathing and ≥1 danger signs) were included. Demographic, clinical, laboratory, and vaccine history data were collected. We assessed associations between characteristics and pneumonia severity and mortality using multivariable logistic regression.

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